In Tokyo, the freelancer cameraman Takuyoshi Masuoka is obsessed investigating the fear sensation near death. When he shots with his camera a man stabbing himself in the eye in the access to the subway, he seeks what the suicidal might have seen to experiment the same sense of horror the man felt when he died. He finds a passage to the underground of Tokyo where he meets a mysterious naked woman that does not speak and he calls her F. He brings F to his place and he has difficulties to feed her, until he discovers that she drinks blood. Masuika becomes a serial killer draining the blood of his victims to nurse F.

Its streets overrun with children, the village of Kaname has distinguished itself with the highest birth rate in Japan. Its citizens are excited-tomorrow, the Prime Minister arrives to formally celebrate Kaname's demographic distinction. The spirit is festive, except for one 14-year-old girl. She knows the secret of Kaname's fecundity, and she's typing up a tell-all letter to a prominent journalist, revealing the crazy, complicated tale. It all began 14 years ago... Betrayed and disgraced, big-city reporter Kazuya Mizuno is banished to a desk at Kaname's boring little town newspaper. But Kaname isn't as boring as it seems on the surface. Not with characters around like Shimeko, a girl genius with a childlike lack of propriety, and her ace fisherman/folk-singer dad. Or the overbearing and unpleasant local Shinto priest, a former Christian cultist. Or Endo, Kazuya's new colleague...